• Supports AMD^® RYZEN™ THREADRIPPER™ Series Processors
• Support 8 DIMMs, Quad Channel DDR4 3600+ (OC)
• DDR4 Boost: Advanced technology provided by MSI OC lab to ensure maximum compatibility for overclocking performance.
• AUDIO BOOST 4: Reward your ears with studio grade sound quality for the most immersive audio experience
• Mystic Light and Mystic Light Sync: Personalize your PC with 16.8 million colors / 17 effects controlled in one click with the Mystic Light APP or a mobile device.
• Professional IO cover & heatsink: Stunning looks, protecting the I/O ports
• EZ Debug LED: Easiest way to troubleshoot
• Lightning Fast Game experience: 3 x Turbo M.2 , 1 x M.2 Shield, and Lightning USB 3.1 Gen2
• Lightning USB: Double bandwidth, supports USB 3.1 Gen2 Type A + Type C
• PCI-E Steel Armor: Protecting VGA cards against bending and EMI
• X-Boost: Great tool to boost your USB & Storage performance
• Double ESD Protection: Double layer grounding motherboard mounting holes
• Military Class 6, Guard-Pro: Latest evolution in high quality components for best protection and efficiency
• Click BIOS 5: Award-winning BIOS with high resolution scalable font, favorites and search function
• VR Ready: Best virtual reality game experience without latency, reduces motion sickness

MAKING YOUR LIFE EASIER IS OUR BUSINESS
Combining quality you can rely on with top performance and clever business solutions are key aspects of the MSI PRO SERIES motherboards. Engineered to gratify even the most demanding professional, these motherboards will fit in any PC. Making your life easier and supporting your business with super stable, reliable and long-lasting top performance.


X399 SLI PLUS

STRONGER THAN STEEL


Clear CMOS & BIOS FLASHBACK+ button
PS/2 Combo & USB 2.0 Port
8 x USB 3.1 Gen1
LAN Port & Lightning USB 3.1 Gen2 Type A+C
Golden audio jacks with S/PDIF
Mystic Light RGB Cover
Change up to 16.8 million colors & 17 LED effects
Heavy plated heatsinks
Leading heatsink design, for maximum cooling
Mystic Light RGB heatsink
Change up to 16.8 million colors & 17 LED effects
DDR4 Boost
Optimized traces and isolated memory circuitry
PCI-E Steel Armor
Protecting VGA cards against bending and EMI
Triple Turbo M.2 & 1 x M.2 Shield
NVMe support, up to 32 Gb/s using PCI-Express Gen3 x4
Audio Boost 4 with amplifier
Optimized audio using the best components, 120 dB SNR 32-bit


MYSTIC LIGHT

PERSONALIZE YOUR GAMING RIG
Customize and set up your own color scheme with MSI Mystic Light utility. Select the available colors from the palette to match your system style. Bored of the same colors? Simply change the complete look of your system in 1 second!


No animation


Breathing


Flashing


Double Flashing


Random


Stack


Wave / Marquee


CPU Tempera
ture


Meteor


Lightning


Rainbow


POP


RAP


JAZZ


Play


Movie


Off


Msi-X399-SLI-PLUS
Extendable
Remote control
Mystic Light sync
LEARN MORE ABOUT MYSTICLIGHT
COOLING

STAY COOL
Cooling your PC is essential for reliable performance. We've made sure to include enough fan headers with full control to allow you to cool your system to the max.


6x fan headers
Full fan control
Watercooling ready
LEARN MORE ABOUT COOLING

DISPLAY

ENJOY THE LATEST VIDEO STANDARDS
Supporting the latest display connectors for new technologies (OLED, HDR) and legacy connectors for beamers, MSI motherboards are designed to make life easier for any professional user.

Multi-GPU
LEARN MORE ABOUT DISPLAY

STORAGE

BE THE FIRST TO BOOT UP IN THE MORNING
This MSI product supports all the latest storage standards. This allows you to connect any ultra-fast storage device, giving you noticeable benefits. Start programs faster, load data faster and increase productivity.

M.2 Shield
3x M.2
Boost your storage
LEARN MORE ABOUT STORAGE

AUDIO

PROFESSIONAL SOUND QUALITY
Get the most immersive sound experience. MSI Audio Boost delivers the highest sound quality through the use of premium quality audio components. This lets you enjoy breathtaking, game-changing sound to create the most dynamic soundscapes.

Audio Boost 4
Audio amplifier
Audio capacitors
LEARN MORE ABOUT AUDIO

VR

IMMERSE YOURSELF INTO VIRTUAL WORLDS
Integrating the very best of cutting edge technologies on MSI hardware provides a smooth VR ride. Through joint efforts with major VR brands, combined with unique MSI features geared to VR, MSI brings gamers and VR professionals a vivid and realistic experience in which content truly comes alive.

One click VR
LEARN MORE ABOUT VR READY

NETWORK

STABLE, SECURE & FAST NETWORKING
Optimized for professional and multimedia use, this generation comes equipped with a high quality network solution ready to serve you with 24/7 reliability when transferring big data.

Intel®LAN
Bandwidth management
LAN protect
LEARN MORE ABOUT NETWORK
MEMORY

UNMATCHED MEMORY PERFORMANCE
MSI motherboards are crammed with features to fuel your system's memory with more speed, higher overclockability and increased stability.


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Optimal layout
DC/PWM mode
100% compatibility
A-XMP
LEARN MORE ABOUT MEMORY

EXTREME PERFORMANCE

DESIGNED FOR OVERCLOCKING
Combining industries best components with MSI’s top notch R&D design, you can count on this motherboard to deliver world class performance. System tuning and troubleshooting tools are at your disposal to push your system to new heights.

13 PHASE POWER DESIGN
For power users
LEARN MORE ABOUT TUNING

USB 3.1

X Boost
USB

MAXIMIZE YOUR USB DEVICE PERFORMANCE
Transfer lots of data, music and movies over USB faster than ever. MSI offers a wide variety of options to connect and boost your USB 3.1 devices, delivering lightning-fast transfer speeds!

Double bandwidth USB 3.1
Reversible Type-C connector
Front USB 3.1
Boost your USB
LEARN MORE ABOUT USB
SOFTWARE

APPS TO GREATLY IMPROVE EFFICIENCY
With years of experience in creating performance enhancing tools that are easy to use, only the highest quality applications are at your disposal. Use these tools to get the most out of your motherboard and time spent.


X-Boost
Command Center
Live Update
RAMDisk
LEARN MORE ABOUT SOFTWARE
QUALITY & PROTECTION

BUILT ON EVERLASTING QUALITY
Using only the finest quality components and integrating the latest technological innovations delivers the best possible professional experience. Rigorous quality testing under the most extreme conditions ensures a super reliable, long-lasting and high performance motherboard.


M.2 Shield
Steel Armor
Military Class 6
Windows 10 certified
LEARN MORE ABOUT QUALITY
BIOS

A USER-FRIENDLY BIOS
We made sure our BIOS contains all the latest options and is easy to use for everyone. The extensive features found in CLICK BIOS 5 let you fine-tune your system to deliver reliable maximum performance.






Easy/advanced mode
Convenient search
Hardware monitor
LEARN MORE ABOUT BIOS
3D PRINTING & MODDING

FIRE YOUR IMAGINATION!
Create your own unique modifications for MSI motherboards! MSI supports 3D-printable parts for personalization. With various design offered by MSI MOD HUB, you are able to easily customize heatsink covers, SLI bridges, and even your own name plates and logos in your favorite colors and materials.